Week 4 delivered comebacks, major upsets and a changing playoff picture, with several teams making powerful statements heading into October.
Game of the Week — Patriots stun Bills
The New England Patriots defeated Buffalo 29–26, handing the Bills their first loss of the season.
Drake Maye threw three touchdown passes, including the late go-ahead score to Efton Chism, before New England’s defense closed out the victory with a crucial late interception.
Cowboys rally past Texans
Dallas erased a 10-point halftime deficit to defeat Houston 34–30.
CeeDee Lamb was spectacular with 17 receptions for 189 yards and the game-winning touchdown, while Javonte Williams scored three rushing touchdowns.
Houston dropped to 0–4.
Rams complete comeback in Philadelphia
The Los Angeles Rams overcame a 10-point deficit and scored 14 unanswered fourth-quarter points to beat the Eagles 24–20.
Philadelphia managed only 172 total yards as Los Angeles finished with 415.
Chiefs remain unbeaten
Kansas City survived Las Vegas 30–27 in a thrilling AFC West battle.
Kenneth Walker III ran for 177 yards and two touchdowns, while Patrick Mahomes earned his 99th regular-season victory.
The Chiefs improved to 4–0.
49ers stay perfect
San Francisco defeated Denver 24–14, moving to 4–0.
The 49ers continued to look like one of the NFC’s most complete teams, while Denver fell to 2–2.
Vikings improve to 4–0
Minnesota defeated Miami 15–10, becoming one of the NFL’s remaining unbeaten teams.
T.J. Hockenson had 13 receptions for 119 yards, while the Dolphins fell to 0–4.
Panthers shock Lions
Carolina defeated Detroit 32–26 in Sunday Night Football.
Bryce Young threw two touchdown passes to Tetairoa McMillan, who exploded for 14 catches, 192 yards and two touchdowns.
Chuba Hubbard added 122 rushing yards and two scores.
Other Week 4 Results
Browns 27, Steelers 24
Giants 36, Cardinals 24
Colts 30, Commanders 13
Bears 23, Jets 12
Jaguars 22, Bengals 17
Packers 17, Buccaneers 14
Ravens 24, Titans 18
Seahawks 30, Chargers 23
Chiefs 30, Raiders 27
49ers 24, Broncos 14
Panthers 32, Lions 26
Week 4 Winners
Kansas City Chiefs: Still undefeated and sitting atop the AFC West.
San Francisco 49ers: Another convincing win keeps them among the NFC’s elite.
Minnesota Vikings: A perfect 4–0 start has turned Minnesota into a serious contender.
New England Patriots: The Buffalo upset could be a defining moment for the season.
Dallas Cowboys: A dramatic comeback prevented an 0–4 start.
Week 4 Losers
Houston Texans: Falling to 0–4 despite leading Dallas by 10 at halftime.
Miami Dolphins: Now 0–4 and searching for answers offensively.
Los Angeles Chargers: Their 30–23 loss to Seattle dropped them to 0–4.
Philadelphia Eagles: Blowing a fourth-quarter lead at home leaves Philadelphia at 2–2.
Detroit Lions: A defense that surrendered 445 yards remains a major concern.
Week 4 Takeaway
The NFL is beginning to separate into contenders and teams already facing serious problems.
Kansas City, San Francisco and Minnesota remain unbeaten, while Buffalo, Philadelphia and Detroit suffered losses that could prove important later in the season.
The biggest surprise may be New England’s victory in Buffalo, while Dallas’ comeback and Carolina’s Sunday-night performance provided two of the weekend’s most impressive wins.